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Introduction

An introduction to the science of making chemical measurements. Learn the fundamentals of information and sample gathering, measuring, and minimizing experimental error. We’ll cover the elementary statistics needed to understand chemical measurements, followed by proper use of calibrations.

Explore the principles of how chromatographs achieve chemical separations, which will help optimize your analyses.

Lastly, we’ll cover the principles of spectroscopy, which form the basis for understanding how FTIR and UV/Vis spectrometers identify and quantify molecules. Exercises and homework are used to increase the retention of knowledge.

Learn the three variables used to optimize analyses.
See how to quantify and minimize measurement error.
Learn how a chromatograph works and how to improve your separations.
Discover how infrared and UV/Vis spectrometers work and how to use them to solve industrial problems.

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Principles of Analytical Chemistry Module 1

Module 1

What Is Analytical Chemistry?

Optimizing Analyses
Becoming a Problem Solver
Sampling
Significant Figures

Quantifying Measurement Error

Random Error and Its Sources
- Signal-to-Noise Ratios
- Getting Rid of Noise
Systematic Error
Precision and Accuracy

Principles of Analytical Chemistry Module 2

Module 2

Quantifying Measurement Error (continued)

Calibrations
- Calibration Checks
- Calibration Applicability

Statistics for Chemical Measurement

Mode, Median, Mean
The Standard Deviation
Confidence Limits

Introduction to Chromatography

Basic Theory
Modeling a Separation

Principles of Analytical Chemistry Module 3

Module 3

Introduction to Chromatography (continued)

Peak Widths
Resolution
Optimizing Separations
Gas Chromatography (GC)
High Pressure Liquid Chromatography (HPLC)

Principles of Spectroscopy

The Properties of Light

Principles of Analytical Chemistry Module 4

Module 4

Principles of Spectroscopy (continued)

Fourier Transform Infrared Spectroscopy (FTIR)
- Instrumentation
- Sample Preparation: ATR
Ultraviolet-Visible (UV-Vis) Spectroscopy
- Theory
- Instrumentation